Hormone therapy for Prostate cancer is one of the ways to recover this disease. Actually there are many ways to cure this cancer like surgery and chemotherapy. Surgery have two possibilities, it may remove whole prostate gland or remove few part of prostate gland. For removing whole part of gland, thing to be considered is whether the cancer has experienced metastatic or not. Doctor will do some test to know the best way to recover patient, so do chemotherapy. Each treatment has its own side effects. In this article, we will emphasize in hormone therapy.
Knowing about hormone therapy for prostate cancer
Before knowing about hormone therapy for prostate cancer, first we have to know what the relation between cancer cells and hormone is. How hormone can trigger growing of cancer cells. Well, hormone is a substance which is produced by endocrine gland inside our body. Hormone bound receptor on the surface of cancer cell and trigger cell to cleave itself. That is what makes cancer to grow. Testosterone which is produced by testicle stimulates prostate cancer. That is why; hormone therapy became one of treatment to cure this disease. Hormone therapy blocks body to produce hormone or slow down its activity.
How is hormone therapy for prostate cancer given? Hormone therapy is done by giving medicine which block or slow down the producing of testosterone. As testosterone is like a fuel to cancer cells. Other way is by blocking testosterone effect or anti-androgen, it hampers the bundling of dehidrotestosteron (DHT) with androgen receptor. Empowering androgen blockade by intracellular way is also the option. In some cases, doctor will combine those ways. Drugs which are given for hormone therapy usually are leoprolid and goserelin (block testis to produce testosteron), flutamide, bicalutamide, and nilutamide (anti-androgen), other drugs which are given are ketoconazole and aminogluthetimide.
Hormone therapy for prostate cancer is given if; the patient has higher risk of recurrence, prostate cancer have experienced metastatic and if patient mind to have surgery or radiotherapy. Therefore, patient does not need to have surgery if they are treated with hormone therapy. Hormone therapy also lessen the recurrence of cancer, because it lost the ‘fuel’ of cancer, so cancer cells grow so slowly and controllable in several years. However, there are also some side effects that are caused by hormone therapy.
This treatment also has several side effects like higher risk of kidney disorder. This research is got when researcher from McGill University checked 10.250 patients which is given hormone therapy in 1997-2008. Each participant was followed up during 4 years after they were diagnosed of prostate cancer. The result was 232 participants were experienced acute kidney disorder. By this research, doctor is suggested to check kidney condition of their patient before doing hormone therapy. Other side effects of losing androgen are fatigue, weak, loss of sexual libido, hot flush or burning feel on the face, and anemia. To do hormone therapy, it is better to ask your doctor to prevent worse side effects of hormone therapy for prostate cancer.